A smarter path to lasting weight loss.

Semaglutide and tirzepatide are medications classified as GLP-1 receptor agonists. They help regulate appetite and blood sugar levels, making them effective treatments for weight loss and managing type 2 diabetes.

Semaglutide mimics the GLP-1 hormone, which reduces hunger and increases feelings of fullness. Tirzepatide targets both GLP-1 and GIP receptors, providing enhanced appetite suppression and blood sugar regulation.

Candidates typically include individuals with a BMI of 30 or higher, or those with a BMI of 27 or higher who have weight-related health conditions such as type 2 diabetes or hypertension. At TransformRX we believe that those with even lower BMI may benefit long-term with this program, hence a thorough medical evaluation will determine if you are a suitable candidate.

Both medications are administered via a once-weekly injection. Our healthcare professionals will teach you how to self-administer these injections at home. If you prefer, you can also come to our clinic to have your injection administered.

During your initial consultation, we will conduct a comprehensive health evaluation, review your medical history, and discuss your weight loss goals. You will also have some blood drawn for important baseline lab values, as well as a Body Composition Analysis with a very advanced analyzer. Based on this assessment, we will develop a personalized treatment plan that includes the appropriate dosage of semaglutide or tirzepatide.

Follow-up appointments are typically scheduled every 4 weeks to monitor your progress, adjust your treatment plan if necessary, and provide ongoing support and motivation.

While individual results may vary, A very recent and large study published in JAMA showed that patients using semaglutide lost an average of 5.8% of their body weight over 6 months and 8.3% over 12 months. In this same study, tirzepatide users experienced even greater weight loss, with 10.1% body weight loss at 6 months and 15.3% at 12 months.(1) This means that tirzapetide can cause almost twice the weight loss at 6 and 12 months versus semaglutide.

In addition to weight loss, semaglutide and tirzepatide can improve blood sugar control, lower the risk of cardiovascular disease, enhance metabolic function, and reduce chronic inflammation. Most recently, they have been shown to reduce the risk of a number of cancers as well.(2)

Common side effects include gastrointestinal issues such as nausea, vomiting, diarrhea, belching, or fatigue, which typically decrease over time. Some patients may also experience mild pain or redness at the injection site. We are very conscious of side effects such as muscle loss (sarcopenia) and skin laxity (“Ozempic face”) and can offer you ways to minimize this.

Our healthcare team will provide strategies to manage any side effects and ensure your comfort throughout the treatment. If side effects persist or worsen, adjustments to your dosage or treatment plan may be necessary.

The duration of your treatment will depend on your individual weight loss goals and health needs. Our healthcare professionals will work with you to determine the appropriate length of treatment and any necessary adjustments along the way. However, it is important to remember that if you discontinue your treatment for more than a few weeks, you will likely regain the weight you had lost.

In most cases, yes, but it’s important to discuss all medications and supplements you are taking with our healthcare team to ensure there are no potential interactions.

At TransformRX, we provide comprehensive support that includes regular consultations, nutritional counseling, behavioral coaching, and access to educational resources to help you achieve your weight loss goals.