Tru Niagen

Oral Supplementation For Boosting NAD+ Levels

What is Tru Niagen?

Tru Niagen is an oral supplement containing nicotinamide riboside (NR), a precursor to nicotinamide adenine dinucleotide (NAD+), a vital coenzyme found in all living cells. NAD+ plays a crucial role in cellular energy production, DNA repair, and overall metabolic health. As we age, NAD+ levels naturally decline, contributing to the aging process and a decrease in cellular function.

Z

Reducing Appetite

Feel fuller for longer, making it easier to stick to a healthy eating plan.
Z

Regulating Blood Sugar Levels

Maintain stable blood sugar levels to support overall health and reduce cravings.
Z

Boosting Metabolism

Increase your body’s ability to burn fat and maintain a healthy weight.
Tru Niagen

The Science & Mechanism of Action

Z

Nicotinamide Riboside (NR):

Tru Niagen’s active ingredient is NR, a form of vitamin B3 (niacin) that is converted to NAD+ inside the body. NR is more efficient at increasing NAD+ levels than other precursors such as niacinamide or nicotinic acid.
Z

Conversion to NAD+:

  • NR is absorbed into the bloodstream after ingestion.
  • Inside cells, NR is converted into nicotinamide mononucleotide (NMN), which is then transformed into NAD+.
  • Increased NAD+ boosts cellular energy production, supports repair processes, and enhances overall metabolic function.

Pertinent Studies & Research

1. Studies

Multiple studies have shown that oral NR supplementation effectively increases NAD+ levels significantly, depending on dose, after daily use for several weeks.

  • Conze et al. (2019): A randomized, placebo controlled, double-blinded study demonstrated that consumption of 100, 300 and 1000 mg NR dose-dependently and significantly increased whole blood NAD+ (i.e., 22%, 51% and 142%) and other NAD+ metabolites within 2 weeks.
  • Martens et al. (2018):A clinical study demonstrated that NR supplementation safely increased NAD+ levels and showed potential benefits in cardiovascular health and aging by improving blood pressure in older adults.
  • Airhart et al. (2017): This study showed NR significantly elevated NAD+ in healthy middle-aged adults and supported enhanced mitochondrial function and energy production.

2. Metabolic and Aging Research

Research suggests that NAD+ levels impact age-related conditions, such as:

  • Mitochondrial dysfunction (loss of energy production)
  • DNA damage repair efficiency
  • Cognitive decline and neurodegenerative diseases
  • Muscle function and metabolism

Benefits of Increasing NAD+ Levels with Tru Niagen

E

Cellular Energy Production:

NAD+ is crucial for the mitochondria (the “powerhouse” of cells) to produce ATP, the body’s main energy source. Increasing NAD+ improves cellular energy efficiency, reducing fatigue and enhancing endurance.
E

DNA Repair:

NAD+ activates PARP (poly-ADP-ribose polymerase), enzymes responsible for repairing damaged DNA, promoting longevity and maintaining cell health.
E

Cognitive Health:

NAD+ supports brain health by fueling neuronal repair and protecting against age-related cognitive decline, including neurodegenerative conditions like Alzheimer’s disease.
E

Improved Muscle Function:

Research has shown that increased NAD+ levels can enhance muscle strength and function, particularly in older individuals, by improving mitochondrial performance.
E

Metabolic Health:

NAD+ plays a role in metabolism regulation. Elevated NAD+ levels may improve insulin sensitivity and support healthy weight management.
E

Anti-Aging Properties:

By replenishing NAD+, Tru Niagen may help combat the visible and cellular effects of aging, promoting healthier skin, increased vitality, and longer lifespan at the cellular level.

Safety and Side Effects

Safety Profile:

Tru Niagen has undergone rigorous safety studies and has been shown to be well-tolerated in humans, even at high doses. It has received “Generally Recognized as Safe” (GRAS) status from the FDA. It is also NSF Certified for Sport as a safe supplement that is not banned in most professional or collegiate sports.

Mild Side Effects:

Some individuals may experience mild side effects such as:

  • Nausea or digestive discomfort (rare)
  • Mild flushing or skin reactions (though less common compared to niacin)
  • Temporary fatigue as the body adjusts to the supplement

Summary

Tru Niagen is a scientifically backed supplement designed to increase NAD+ levels, thereby enhancing cellular energy, promoting DNA repair, and supporting overall metabolic and cognitive health. With a growing body of research demonstrating its potential anti-aging benefits and safety, Tru Niagen offers an effective way to boost NAD+ levels and support healthy aging.